The Time Course Of Dorsal And Rostral-Ventral Anterior Cingulate Cortex Activity In The Emotional Stroop Experiment Reveals Valence And Arousal Aberrant Modulation In Patients With Schizophrenia

Feroz, Farah Shahnaz and Leicht, Gregor and Rauh, Jonas and Mulert, Christoph (2019) The Time Course Of Dorsal And Rostral-Ventral Anterior Cingulate Cortex Activity In The Emotional Stroop Experiment Reveals Valence And Arousal Aberrant Modulation In Patients With Schizophrenia. Brain Topography, 32. pp. 161-177. ISSN 0896-0267

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Abstract

This paper aims to investigate the temporal dynamics within the dorsal anterior cingulate cortex (dACC) and the rostralventral (rv) ACC during the interaction of emotional valence and arousal with cognitive control in patients with Schizophrenia(SZ) Although cognitive deficits in SZ are highly relevant and emotional disturbances are common,the temporal relationship of brain regions involved in the interaction of emotional and cognitive processing in SZ is yet to be determined. To address this issue,the reaction time (RT),event-related potential (ERP) and temporal dynamics of the dACC and rvACC activity were compared between SZ subjects and healthy controls (HC),using a modified emotional Stroop experiment (with factors namely congruence,arousal and valence). EEG was recorded with 64 channels and source localisation was performed using the sLORETA software package. We observed slower initial increase and lower peaks of time course activity within the dACC and rvACC in the SZ group.In this particular group,the dACC activity during late negativity was negatively correlated with a significantly higher RT in the high arousal conflict condition.In contrast to HC subjects,at the N450 window,there was no significant valence (ERP and rvACC ROI) modulation effect in the SZ subjects.Using high density EEG and source localisation,it was possible to distinguish various disturbances within the dACC and rvACC in patients with SZ,during emotion–cognition processing.

Item Type:	Article
Uncontrolled Keywords:	Schizophrenia, Emotion–cognition, Dorsal anterior cingulate cortex, Rostral-ventral anterior cingulate cortex, Arousal, Valence
Subjects:	Q Science > Q Science (General) Q Science > QP Physiology
Divisions:	Faculty of Electronics and Computer Engineering
Depositing User:	Mohd. Nazir Taib
Date Deposited:	08 Jul 2019 04:03
Last Modified:	30 Aug 2021 02:01
URI:	http://eprints.utem.edu.my/id/eprint/22993
Statistic Details:	View Download Statistic

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