In-Vitro Apatite Growth On Porous Â-Tricalcium Phoshpate Scaffolds Coated With PHVB

Mustafa, Zaleha and Ishak, Nor Fatiha and Othman, Radzali and Ahmad, Nor Naimah Rosyadah and Abd Rahim, Toibah and Sheikh Md Fadzullah, Siti Hajar and Tanner, K. Elizabeth (2018) In-Vitro Apatite Growth On Porous Â-Tricalcium Phoshpate Scaffolds Coated With PHVB. Journal Of Advanced Manufacturing Technology, 12. pp. 135-146. ISSN 2289-8107

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The bioactive properties of polyhydroxybutyrate-co-valerate (PHBV) coated beta-tricalcium phosphate (β-TCP) have been studied invitro. Porous β-TCP scaffolds have been prepared using a template method and sintered at 1450 °C.The bio ceramics were then coated with PHBV solution before being immersed for 6 weeks in a simulated body fluid (SBF)at 37°C.At the end of the immersion time, insignificant changes in the SBF pH value was observed, suggesting good stability against hydrolytic degradation. X-ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR) analyses revealed the presence of apatite.Morphological analysis by SEM showed the formation of apatite crystals in the form of flakes and globular deposits on the scaffold surface.This bonelike apatite indicates good biological activity of the bio ceramics scaffold with PHVB coating suggesting that the composite has potential for bone tissue engineering applications.

Item Type: Article
Subjects: T Technology > T Technology (General)
T Technology > TS Manufactures
Divisions: Faculty of Manufacturing Engineering
Depositing User: Mohd. Nazir Taib
Date Deposited: 07 May 2019 07:33
Last Modified: 02 Jul 2021 15:43
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